Genomic imprinting maintains a reserve pool of blood-forming stem cells in mouse bone marrow

Wednesday, July 17, 2013 - 20:20 in Biology & Nature

Hematopoietic stem cells -- bone marrow-derived adult stem cells that give rise to the wide variety of specialized blood cells -- come in two flavors: the reserve force sits quietly waiting to be called upon while the active arm continually proliferates spawning billions of blood cells every day. In a new study, researchers reveal a new mechanism that is critical in maintaining the delicate balance between the two.

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