Faster, smarter and cheaper drug discovery
Thursday, March 21, 2013 - 22:00
in Biology & Nature
Computers are now sifting through drug libraries to pick out compounds likely to clobber TB with minimal side effects to humans. Programmers have ‘taught’ the computers to understand which chemical features of a drug are associated with efficacy against TB and which are associated with toxicity to mammalian cells. The process may lead to much less trial and error in finding new therapies. The computers even rediscovered a compound reported 40 years ago to have anti-TB activity but since forgotten.