Mouse models fail to reproduce inflammatory genomic response to serious injuries
Monday, February 11, 2013 - 22:00
in Biology & Nature
Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to a new article. The report from a national consortium investigating the role of inflammation in the body's response to injury finds little correlation between the human response to burns, trauma or a bacterial toxin and that of currently used mouse models for those conditions.