Research shows immune system response is detrimental to novel brain cancer therapy

Wednesday, December 5, 2012 - 00:31 in Health & Medicine

For the first time, researchers have demonstrated that the response of natural killer (NK) cells is detrimental to glioblastoma virotherapy, a novel way of treating malignant brain cancer by injecting a virus into the tumor. A number of clinical trials are currently underway to test whether glioblastoma virotherapy will facilitate antitumor efficacy, but new research shows that in pre-clinical models, NK cells are killing off the virus – infected cells, thus rendering the therapy less effective.

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