Genetic factor holds key to blood vessel health

Monday, November 19, 2012 - 22:31 in Health & Medicine

Researchers have identified a genetic factor that prevents blockages from forming in blood vessels, a discovery that could lead to new therapies for cardiovascular diseases. Researchers found that a shortage of the genetic factor KLF4, which regulates endothelial cells lining the interior of blood vessels, makes the lining more prone to the buildup of plaque and fat deposits. Further, the deficiency made the blood vessel more susceptible to clot formation.

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