Replicating risk genes in bipolar disorder
Monday, October 15, 2012 - 09:31
in Health & Medicine
One of the biggest challenges in psychiatric genetics has been to replicate findings across large studies. Scientists have now performed one of the largest ever genetic replication studies of bipolar affective disorder, with 28,000 subjects recruited from 36 different research centers. Their findings provide compelling evidence that the chromosome 3p21.1 locus contains a common genetic risk for bipolar disorder, the PBRM1 gene.