Aggressive cancer exploits Myc oncogene to amplify global gene activity
Thursday, September 27, 2012 - 20:00
in Health & Medicine
Researchers have determined the mechanism used by c-Myc to increase the expression of all active genes in cancer cells. Elevated levels of c-Myc are linked to increased rates of metastasis, disease recurrence, and mortality in cancer patients. Guided by this new model, researchers hope to find ways to restrict c-Myc’s activity to eradicate cancer cells that become dependent on c-Myc for their survival.