Study pinpoints epigenetic function of common cancer-causing protein: It's not what science thought
Wednesday, September 26, 2012 - 10:00
in Biology & Nature
"This is a potent oncogene whose mechanism we thought we knew. But basically in this paper we demolish the accepted model. DNp63a doesn't work through p53 – it operates through epigenetic silencing of anti-proliferative genes," says the study's senior author, Joaquin M. Espinosa, Ph.D.