Neurodegenerative diseases: New findings on protein misfolding

Misfolded proteins can cause various neurodegenerative diseases such as spinocerebellar ataxias or Huntington's disease, which are characterized by a progressive loss of neurons in the brain. Researchers have now identified 21 proteins that specifically bind to the protein ataxin-1. Twelve of these proteins enhance the misfolding of ataxin-1 and thus promote the formation of harmful protein aggregate structures.

Read the whole article on Science Daily

More from Science Daily