Early menopause: A genetic mouse model of human primary ovarian insufficiency

Thursday, August 30, 2012 - 11:02 in Biology & Nature

Scientists have established a genetic mouse model for primary ovarian insufficiency (POI), a human condition in which women experience irregular menstrual cycles and reduced fertility, and early exposure to estrogen deficiency. POI affects approximately one in a hundred women. In most cases of primary ovarian insufficiency, the cause is mysterious, although genetics is known to play a causative role.

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