Blocking destruction of defective proteins unexpectedly delays neurodegeneration in mice

Wednesday, August 15, 2012 - 14:30 in Biology & Nature

One might expect that ridding a brain cell of damaged proteins would be a universally good thing, and that impairing the cell's ability to do this would allow the faulty proteins to accumulate within the cell, possibly to toxic levels. So a lot of scientific effort has gone into looking for ways to enhance the process by which cells dispose of banged-up proteins. But this thinking may need some revision, according to a new study.

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