Mechanism of lung cancer-associated mutations suggests new therapeutic approaches
Monday, July 30, 2012 - 21:00
in Health & Medicine
Researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors. The investigators found that the protein encoded by this gene, called EPHA3, normally inhibits tumor formation, and that loss or mutation of the gene -- as often happens in lung cancer -- diminishes this tumor-suppressive effect, potentially sparking the formation of lung cancer.