An error-eliminating fix overcomes big problem in '3rd-gen' genome sequencing
Sunday, July 1, 2012 - 15:31
in Biology & Nature
A team has developed a software package that fixes a serious problem inherent in "3rd-gen" single-molecule genome sequencing: the fact that every fifth or sixth DNA "letter" it generates is incorrect. The high error rate is the flip side of the new method's chief virtue: it generates much longer genome "reads," providing a much more complete picture of genomes.