Friendly-to-a-fault, yet tense: Personality traits traced in brain

Friendly to a fault, yet tense? A personality profile marked by overly gregarious yet anxious behavior is rooted in abnormal development of a circuit hub buried deep in the front center of the brain. Brain scans pinpointed the suspect brain area in people with Williams syndrome. Matching the scans to their scores on a personality rating scale revealed that the temperament traits correlated with abnormalities in the brain structure, called the insula.

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