Disarming the botulinum neurotoxin
Friday, February 24, 2012 - 21:30
in Biology & Nature
Researchers have discovered how botulinum neurotoxin, a potential bioterrorism agent, survives the hostile environment in the stomach on its journey through the human body. Their study reveals the first 3D structure of a neurotoxin together with its bodyguard, a protein made simultaneously in the same bacterium. This new information reveals the toxin's weak spot -- a point in the journey that can be targeted with new therapeutics.