How cells dispose of their waste: Researchers reveal the structure of the cellular protein degradation machinery

Monday, January 23, 2012 - 17:20 in Biology & Nature

Defective proteins that are not disposed of by the body can cause diseases such as Alzheimer’s or Parkinson’s. Scientists recently succeeded in revealing the structure of the cellular protein degradation machinery (26S proteasome) by combining different methods of structural biology. The results represent an important step forward in the investigation of the 26S proteasome.

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