Melatonin precursor stimulates growth factor circuits in brain

Friday, February 5, 2010 - 00:21 in Biology & Nature

N-acetylserotonin, the immediate precursor to melatonin, activates the same growth circuits in the brain as BDNF (brain-derived neurotrophic factor). The results have implications for how some antidepressants function and suggest that the molecules and pathways involved in mood regulation and circadian rhythms are intertwined.

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