Common mechanism underlies many diseases of excitability

Monday, December 28, 2009 - 18:07 in Biology & Nature

Inherited mutations in voltage-gated sodium channels are associated with many different human diseases, including genetic forms of epilepsy and chronic pain. New research has now determined the functional consequence of three such mutations. These results suggest that there might be a common mechanism underlying diseases caused by mutations in voltage-gated sodium channels.

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