How Stressed Fat Tissue Malfunctions
Tuesday, July 21, 2009 - 22:14
in Health & Medicine
Fat tissue dysfunction is caused by obesity-induced fat tissue stress: Cells over-grow as they store fat which may cause decreased oxygen delivery into the tissue; individual cells may die (at least in mouse models), and fat tissue inflammation ensues. The teams collected fat tissue samples from people undergoing abdominal surgery and identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.