New Human Genetic Link To High Levels Of 'Good' Cholesterol

HDL cholesterol, or "good" cholesterol, helps eliminate excess "bad" cholesterol that might otherwise block arteries. As such, individuals with high plasma HDL cholesterol levels have a decreased risk of coronary artery disease. Researchers now show that mutations in the LIPG gene, which codes for the enzyme endothelial lipase, result in high plasma HDL cholesterol levels, providing important human genetic evidence that inhibition of endothelial lipase is likely to raise "good" cholesterol levels.

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