Big-hearted Fish Reveals Genetics Of Cardiovascular Condition

Monday, March 9, 2009 - 22:28 in Biology & Nature

Researchers have found that a human vascular condition called cerebral cavernous malformation is caused by leaky junctions between cells in the lining of blood vessels. By combining studies with zebrafish and mice, they found that the aberrant junctions are the result of mutated or missing proteins in a novel biochemical process, the so-called "Heart-of-glass" CCM pathway.

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