Structure Of Enzyme Against Chemical Warfare Agents Determined

Sunday, February 1, 2009 - 23:28 in Physics & Chemistry

The enzyme DFPase is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. A detailed understanding of the mechanism by which the enzyme catalyzes chemical reactions is necessary for efforts aiming to improve its properties as a decontaminant. Its structure, which is closely related to its function, has now been determined by neutron diffraction.

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