Researchers find new translocation; weak spots in DNA lead to genetic disease

Friday, July 30, 2010 - 04:21 in Health & Medicine

A genetics research team based at The Children's Hospital of Philadelphia continues to discover recurrent translocations - places in which two chromosomes exchange pieces of themselves. As many as 1 in 600 persons carry balanced chromosome translocations, which involve no loss or gain of DNA. Most such people appear healthy, but may have a child with abnormal chromosome composition and disabilities resulting from disrupted, extra or missing copies of genes...

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