When the smoke clears: Molecular link between tobacco carcinogen and cancer
Wednesday, January 20, 2010 - 10:14
in Health & Medicine
A team of researchers, led by Yi-Ching Wang, at National Cheng Kung University, Taiwan, Republic of China, has uncovered a potential mechanism by which the tobacco-specific carcinogen NNK promotes lung tumour formation and development. Specifically, they suggest that NNK induces the accumulation of a protein known as DNMT1 in the nucleus and that this protein silences genes that suppress tumour formation...