The Hsp90-Antifungal Combo, please: Compromising fungi in the immunocompromised
Wednesday, February 11, 2009 - 02:21
in Health & Medicine
Even the most drug-resistant fungi can be eradicated in multiple in vitro and in vivo models using a lethal combination of an antifungal agent and inhibition of the heat shock protein Hsp90, according to a new study by Whitehead Institute and University of Toronto researchers. The findings could enable development of novel antifungal therapies for patients with compromised immune systems...