In Mice, Alcohol Dependence Results in Brain-Wide Remodeling of Functional Architecture

Wednesday, January 15, 2020 - 10:10 in Biology & Nature

Employing advanced technologies that allow whole brain imaging at single-cell resolution, researchers at University of California San Diego School of Medicine report that in an alcohol-dependent mouse model, the rodent brain’s functional architecture is substantially remodeled. But when deprived of alcohol, the mice displayed increased coordinated brain activity and reduced modularity compared to nondrinker or […]

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