Identification of a novel protein that protects against bowel inflammation
Saturday, September 26, 2015 - 02:50
in Health & Medicine
A group of researchers, led by Prof. MATOZAKI Takashi and Associate Prof. MURATA Yoji at the Kobe University Graduate School of Medicine Division of Molecular and Cellular Signaling, were the first to demonstrate the role of stomach cancer-associated protein tyrosine phosphatase (SAP)-1 in the pathogenesis and prevention of Crohn's disease, ulcerative colitis, and other inflammatory bowel disorders. Their findings, published online ahead of print on July 20, 2015, by the Proceedings of the National Academy of Sciences of the United States of America, are expected to accelerate the development of targeted therapies for inflammatory gastrointestinal diseases.