How the mammoth got its wool: Genetic changes are identified

Monday, July 6, 2015 - 17:30 in Biology & Nature

These are woolly mammoths. Evolutionary change in a gene resurrected in the lab from the extinct woolly mammoth altered the gene's temperature sensitivity and likely was part of a suite of adaptations that allowed the mammoth to survive in harsh arctic environments, according to new research. In a study published in Cell Reports on July 2, 2015, researchers determined the whole-genome sequence of two woolly mammoths and three modern Asian elephants, predicted the function of genetic changes found only in the mammoths, and then experimentally validated the function of a woolly mammoth gene reconstructed in the lab. The research team includes scientists from Penn State University, Nanyang Technological University in Singapore, and the University of Chicago.

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