New gene editing tools force renewed debate over therapeutic germline alteration

Friday, May 1, 2015 - 18:13 in Biology & Nature

Recent evidence demonstrating the feasibility of using novel CRISPR/Cas9 gene editing technology to make targeted changes in the DNA of human embryos is forcing researchers, clinicians, and ethicists to revisit the highly controversial issue of altering the inherited human genome. A provocative Editorial exploring the current technical limitations, safety concerns, and moral acceptability of therapeutic germline gene editing is published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Human Gene Therapy website until May 29th.

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