PRC1 Caught: Cancer-Related Cell Enzyme In Action

A research team has produced a detailed working image of an enzyme in the Polycomb Repressive Complex 1 (PRC1) related to the BRCA1 breast-cancer protein. PRC1 regulates cell development and is associated with many types of cancer because enzymes like PRC1 turn on or turn off the activity of genes in a cell by manipulating individual chromosome units called nucleosomes.  read more

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