Transmitophagy?
Monday, June 16, 2014 - 18:40
in Biology & Nature
Some basic biology may need revising. It's broadly assumed that cells degrade and recycle their own old or damaged organelles, but researchers writing in PNAS say that some neurons transfer unwanted mitochondria, the tiny power plants inside cells, to supporting glial cells called astrocytes for disposal. The researchers looked specifically at the axons of retinal ganglion cells in mice, a type of neuron that transmits visual information from the eye to the brain. The investigation was prompted by observations while studying a mouse model of glaucoma that protein products from the retina were accumulating in the optic nerve head (ONH) just behind the eye. read more