Single dose Ebola vaccine is safe, effective in monkeys against outbreak strain

Friday, August 7, 2015 - 08:30 in Health & Medicine

A single dose of an experimental Ebola virus vaccine completely protects cynomolgus macaques against the current EBOV outbreak strain, EBOV-Makona, when given at least seven days before exposure, and partially protects them if given three days prior, scientists report. The live-attenuated vaccine, VSV-EBOV, uses genetically engineered vesicular stomatitis virus to carry an EBOV gene that has safely induced protective immunity in macaques.

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