New information on Parkinson’s: GDNF not needed by the midbrain dopamine system
Wednesday, March 4, 2015 - 13:20
in Health & Medicine
A key factor in the motor symptoms associated with Parkinson’s disease is the gradual destruction of dopamine neurons. The glial cell-derived neurotrophic factor, or GDNF, has been proven to protect dopamine neurons in test tube conditions and in test animal models for Parkinson’s disease. GDNF and its close relative, neurturin, have also been used in experimental treatments of patients with severe Parkinson’s disease. The results have been promising, but vary widely in terms of efficacy. At the moment, two companies are conducting tests to determine the clinical effects of GDNF on Parkinson’s sufferers.