Genetics underpinning antimalarial drug resistance revealed

Researchers have identified a series of mutations that could help to improve early detection of resistance to our most effective antimalarial drug. The largest genome-wide association study to date of the malaria parasite Plasmodium falciparum unveils a complex genetic architecture that enables the parasite to develop resistance to our most effective antimalarial drug, artemisinin. The results could help to improve early detection of emerging artemisinin resistance.

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