SCNT derived cells, IPS cells are similar, study finds

A team of scientists compared induced pluripotent stem cells and embryonic stem cells created using somatic cell nuclear transfer. They found that the cells derived from these two methods resulted in cells with highly similar gene expression and DNA methylation patterns. Both methods also resulted in stem cells with similar amounts of DNA mutations, showing that the process of turning an adult cell into a stem cell introduces mutations independent of the specific method used.

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