Clues to genetics of congenital heart defects emerge from Down syndrome study
Sunday, October 26, 2014 - 03:30
in Health & Medicine
The largest genetic study of congenital heart defects in individuals with Down syndrome found a connection to rare, large genetic deletions affecting cilia, scientists report. The high risk for congenital heart defects in this group provides a tool to identify changes in genes, both on and off chromosome 21, which are involved in abnormal heart development.