New insights on control of pituitary hormone outside of brain has implications for breast cancer
Sunday, September 30, 2012 - 20:00
in Health & Medicine
Recently, researchers have found that prolactin is also produced by some tissues outside the brain, however little is known about the functions of extra-pituitary prolactin or how its production is regulated in these tissues. The PI3K-Akt oncogenic signaling pathway in the mammary glands of mice rapidly induces cells in the breast itself to produce prolactin, which leads to breast tissue differentiation, and prolactin has long been thought to play a role in breast cancer.