Giving lithium to those who need it

Friday, September 21, 2012 - 10:01 in Health & Medicine

Lithium is a ‘gold standard’ drug for treating bipolar disorder, however not everyone responds in the same way. New research finds that this is true at the levels of gene activation, especially in the activation or repression of genes which alter the level the apoptosis (programmed cell death). Most notably BCL2, known to be important for the therapeutic effects of lithium, did not increase in non-responders. This can be tested in the blood of patients within four weeks of treatment.

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