DNA replication protein also has a role in mitosis, cancer

Monday, May 14, 2012 - 16:30 in Biology & Nature

Scientists have discovered that a protein known as Cdt1, which is required for DNA replication, also plays an important role in a later step of the cell cycle, mitosis. The finding presents a possible explanation for why so many cancers possess not just genomic instability, but also more or less than the usual 46 DNA-containing chromosomes.

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