Separating a cancer prevention drug from heart disease risk
Tuesday, September 13, 2011 - 11:31
in Health & Medicine
Celecoxib reduces the risk of developing precancerous colon polyps, at the cost of increased heart disease risk. By looking closely at how celecoxib acts in the cell, it may be possible to get the benefit without the added risk. Celecoxib inhibits the enzyme GSK3, possibly accounting for its anticancer effects in multiple cell types.