Bone Marrow Transplants: Cancer Drug Shows Promise Against Graft Vs. Host Disease

Wednesday, July 16, 2008 - 11:28 in Health & Medicine

A study in mice suggests the drug SAHA, a new antitumor drug, is also able to reduce the effects of graft-versus-host disease, a common, sometimes fatal complication of bone marrow transplants. SAHA and other HDAC inhibitors also may provide a new way to treat autoimmune diseases. Plans are under way for a U-M trial of the drug in people to prevent graft vs. host disease.

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