Stem Cell-Like Cancer Cells Resistant To Standard Therapy, Responsive To Targeted Therapy

Wednesday, April 30, 2008 - 13:55 in Health & Medicine

A comparison of breast cancer biopsies before and after treatment show that a subset of cells, which have stem cell-like properties, are resistant to standard chemotherapy. Tumors treated with lapatinib, which inhibits a pathway important for self-renewal, retained a smaller fraction of these tumorigenic cells after therapy.

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