New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair

Monday, June 12, 2023 - 15:33 in Biology & Nature

Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair damaged DNA may induce mutations and cell death, eventually leading to the onset of cancer and other diseases. To prevent this, our cells are equipped with various defense systems aimed at finding and repairing damaged DNA.

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