Color-coading gene sequences in human cells

Wednesday, March 4, 2015 - 09:30 in Biology & Nature

(Phys.org)—Is there a way to peer inside the nucleus of a living cell and see how the genes interact? After the completion of the Human Genome Project in 2001, researchers have focused on epigenetic factors, spatial orientation, and non-coding repeated sequences, all of which affect genetic regulation and function. Hanhui Ma and Thoru Pederson from University of Massachusetts Medical School have demonstrated a new technique that resolves the spatial orientation between two target genetic repeated units within a living human cell. Their work is reported in the Proceedings of the National Academy of Sciences.

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