Genetic mechanism discovery key to controlling cell growth in the vinegar fly
Friday, February 20, 2015 - 06:30
in Biology & Nature
A group of researchers of the University of Barcelona (UB) have described a key interaction to understanding growth control in the vinegar fly (Drosophila melanogaster). According to the study, published in the journal of the European Molecular Biology Organization (EMBO), EMBO Reports, the interaction between the transcription factor Cabut and the protein Yorkie (YAP/TAZ in humans) is necessary for tissue and organ regeneration and growth. The study could have biomedical implications as the protein Yorkie is associated with different types of cancer; to avoid the interaction between Cabut and Yorkie could be a potential therapeutic target.