Fluorescent molecular rotors may revolutionize the search for new anticancer drugs

Wednesday, September 24, 2014 - 07:31 in Physics & Chemistry

When Nobel Laureate Sydney Brenner established the A*STAR Molecular Engineering Laboratory five years ago, his aim was to bring together a small team of young, high-caliber researchers from disparate disciplines to catalyze game-changing advances in science and technology. His venture has now borne fruit with the laboratory's development of fluorescent molecular rotors—used for almost 20 years to measure physicochemical properties such as viscosity—to probe the molecular interactions between proteins involved in cancer1.

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