Study comparing tenofovir gel and oral tablet finds gel provides more drug to tissue

In the first study to make head-to-head comparisons between tenofovir gel and oral tenofovir – two promising approaches for preventing HIV in women – researchers found that daily use of the vaginal gel achieved a more than 100-times higher concentration of active drug in vaginal tissue than did the oral tablet, while, compared to the gel, the tablet used daily was associated with a 20-times higher active drug concentration in blood.

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