Putting microRNAs on the stem cell map
Thursday, August 7, 2008 - 13:49
in Biology & Nature
Embryonic stem cells are always facing a choice—either to self-renew or begin morphing into another type of cell altogether. It's a tricky choice, governed by complex gene regulatory circuitry driven by a handful of key regulators known as "master transcription factors," proteins that switch gene expression on or off.