Nanoparticles Deliver 'Suicide Gene' Therapy to Pediatric Brain Tumors Growing in Mice
Wednesday, January 8, 2020 - 09:30
in Health & Medicine
Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals' survival.