"Synthetic" Chromosome Permits Rapid, On-Demand "Evolution" of Yeast

In the quest to understand genomes--how they're built, how they're organized and what makes them work--a team of Johns Hopkins researchers has engineered from scratch a computer-designed yeast chromosome and incorporated into their creation a new system that lets scientists intentionally rearrange the yeast's genetic material. A report of their work appears September 14 as an Advance Online Publication in the journal Nature.

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